PROPIONIC ACID METABOLISM IN MOUSE LIVER SLICES
نویسندگان
چکیده
منابع مشابه
Propionic acid metabolism in mouse liver slices.
Odd carbon fatty acids are considered to be oxidized in tissue by successive fl oxidation in much the same way that even carbon members of the series are (14). The terminal S-carbon unit has been investigated to some extent. Atchley (5) demonstrated propionic acid as an end-product in the oxidation of valeric acid by a rabbit enzyme system. Studies on malonate inhibition with odd carbon fatty a...
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Propionic acid (PA) is a short chain fatty acid, a common food preservative and metabolic end product of enteric bacteria in the gut. The present study was undertaken to investigate the effect of PA on liver injury in male rats. Male western albino rats were divided into two groups. The first group served as normal control, the second was treated with PA. The activities of serum hepatospecific ...
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Ruminant products are the major source of CLA for humans. However, during periods of fat mobilization, the liver might play an important role in CLA metabolism which would limit the availability of the latter for muscles and milk. In this context, rumenic acid (cis-9, trans-11 CLA) metabolism in the bovine liver (n = 5) was compared to that of oleic acid (n = 3) by using the in vitro liver slic...
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The conversion of propionyl coenzyme A to succinyl-CoA involves carboxylation to methylmalonyl-Cob (a), isomerization of methyhnalonyECoA (a) to its enantiomorph methyhnalonylCoA (b), and isomerization of the latter to succinyl-CoA (3). Since methylmalonyl-CoA (a) has recently been shown to have the D configuration (4, 5), the reversible reaction catalyzed by methylmalonyl-CoA racemase will hen...
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While much is known of the various pathways of serine metabolism, there is little quantitative information concerning the relative importance of each. The present study has, therefore, been undertaken to examine the over-all pattern of serine metabolism in surviving rat liver slices. It seems likely that serine is in the major pathway for both the synthesis of glycine and “l-carbon” compounds f...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1952
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)55707-0